Monthly Archive for July, 2010

Healthcare Law Has More Doctors Teaming Up

A surprising rush to form medical alliances could change the quality and costs of treatment.

By Noam N. Levey Los Angeles Times , July 28, 2010

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Tribune Washington Bureau

As Congress debated the healthcare bill, many critics lamented it would do little to transform a system in which doctors and hospitals bounce patients around in an uncoordinated, costly, sometimes tragic process.

But something unexpected has happened since President Obama signed the legislation in March. Spurred in part by the law, many independent providers across the country are racing to mold themselves into the kind of coordinated teams held up as models for improving care.

In some places, the scramble is so intense that physician groups and hospitals are putting aside rivalries and signing new partnerships almost daily.

“It’s kind of like the Oklahoma land rush right now,” said Patrick Carrier, a veteran hospital administrator who heads Christus Santa Rosa, a group of Catholic hospitals in San Antonio. “Everyone has their wagons lined up and they’re getting ready to go.”

Three of San Antonio’s hospital systems are competing to form alliances with local doctors who are giving up their private fee-for-service practices in exchange for paid positions on a hospital’s team.

Healthcare experts have long argued that such a unified approach to medical care offers the best hope for improving quality and saving money.

While a few institutions such as the Mayo Clinic and Kaiser Permanente have thrived doing this, the entrenched, competing interests of providers were widely seen as a barrier to nationwide change.

Read more…

What Do You Lack? Probably Vitamin D

PERSONAL HEALTH

JANE E. BRODY, New York Times, July 26, 2010

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Vitamin D promises to be the most talked-about and written-about supplement of the decade. While studies continue to refine optimal blood levels and recommended dietary amounts, the fact remains that a huge part of the population — from robust newborns to the frail elderly, and many others in between — are deficient in this essential nutrient.

If the findings of existing clinical trials hold up in future research, the potential consequences of this deficiency are likely to go far beyond inadequate bone development and excessive bone loss that can result in falls and fractures. Every tissue in the body, including the brain, heart, muscles and immune system, has receptors for vitamin D, meaning that this nutrient is needed at proper levels for these tissues to function well.

Studies indicate that the effects of a vitamin D deficiencyinclude an elevated risk of developing (and dying from) cancers of the colon, breast and prostate; high blood pressure and cardiovascular disease; osteoarthritis; and immune-system abnormalities that can result in infections and autoimmune disorders like multiple sclerosisType 1 diabetes and rheumatoid arthritis.

Most people in the modern world have lifestyles that prevent them from acquiring the levels of vitamin D that evolution intended us to have. The sun’s ultraviolet-B rays absorbed through the skin are the body’s main source of this nutrient. Early humans evolved near the equator, where sun exposure is intense year round, and minimally clothed people spent most of the day outdoors.

Move to Restrict Pain Killers Puts Onus on Doctors

29pain1-articleinlineIn an unusual move, a state government is developing regulations meant to stop doctors from prescribing higher doses of powerful — and often dangerous — pain killers for patients who are not benefiting from them.

The effort, in Washington State, represents the most sweeping attempt yet to stem what some experts see as the excessive use of prescribed narcotics, and it is being closely watched by medical professionals elsewhere. Among other things, Washington would apparently become the first state that would require a doctor to refer patients on escalating doses of pain killers for evaluation if they were not improving.

Experts in pain treatment and drug abuse prevention say the growing use of long-acting pain killers like OxyContin, fentanyl and methadone has been a crucial factor in a nationwide epidemic of overdose deaths, largely from the abuse of such drugs.

Nationwide, fatalities from prescription drug overdoses are the second-leading cause of accidental death behind car accidents and, in some states, are the leading cause, according to the Centers for Disease Control and Prevention.

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With This Rinse, Performance Improves

20bestspan-articlelargeExercise scientists say they have stumbled on an amazing discovery. Athletes can improve their performance in intense bouts of exercise, lasting an hour or so, if they merely rinse their mouths with a carbohydrate solution. They don’t even have to swallow it.

It has to be real carbohydrates, though; the scientists used a solution of water and a flavorless starch derivative called maltodextrin. Artificial sweeteners have no effect.

And the scientists think they have figured out why it works. It appears that the brain can sense carbohydrates in the mouth, even tasteless ones. The sensors are different from the ones for sweetness, and they prompt the brain to respond, spurring on the athlete.

Many athletes depend on sugary beverages to keep them going. But often, when blood is diverted from the stomach to working muscles during intense exercise, drinks or foods cause stomach cramps. So a carbohydrate rinse can be a way to get the same effect.

“You can get an advantage from tricking your brain,” said a discoverer of the effect, Matt Bridge, a senior lecturer in coaching and sports science at the University of Birmingham in England. “Your brain tells your body, ‘Carbohydrates are on the way.’ ” And with that message, muscles and nerves are prompted to work harder and longer.”

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Gel Found to Reduce AIDS Risk in Women

David Brown Washington Post Staff Writer , July 20, 2010
hiv-vaginal-gel1A woman’s risk of infection with the AIDS virus can be significantly cut by the use of a vaginal gel, a study has found. The research marks the first success in a 15-year search for a way women can independently protect themselves from contracting HIV infection through sex. Short of a vaccine, an effective vaginal microbicide has been the most elusive goal in the epidemic.

The research, which was conducted in South Africa and will be presented Tuesday at the 18th International AIDS Conference in Vienna, tested a gel containing the antiretroviral drug tenofovir. While far from perfect, it was unambiguously helpful, reducing the risk of HIV infection by 39 percent in a group of women who used it for about three-quarters of their sexual encounters. Those who used it more consistently experienced 54 percent fewer infections.

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Amnesty Warns of Healthcare Crisis in North Korea

15 July 2010 BBC

_48359916_korea2North Korea is failing to provide the most basic healthcare needs for its people, Amnesty International warns.

An investigation by the human rights watchdog found barely functioning hospitals, poor hygiene and epidemics made worse by widespread malnutrition. Many people were also too poor to pay for treatment, the report citing North Koreans and health workers said.

Pyongyang spends less than $1 (£0.65) per person on healthcare a year, World Health Organization figures show.

Amnesty’s report, The Crumbling State of Health Care in North Korea, is based on interviews with more than 40 North Koreans, who left the country between 2004 and 2009.

Health professionals who work with North Koreans were also consulted.

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Health Care

Health Reform

Building on a year’s work from the House and the Senate, the final health reform legislation that the President signed into law included theunknown best ideas from both sides of the aisle offered in the course of the debate.

Health reform will make health care more affordable, make health insurers more accountable, expand health coverage to all Americans, and make the health system sustainable, stabilizing family budgets, the Federal budget, and the economy:

Read more…

Cancer Genome Project Team Releases Preliminary Treatment Response Data

GenomeWeb Daily News, July 15, 2010

NEW YORK (GenomeWeb News) – Researchers involved with the Cancer Genome Project announced today that they are releasing treatment response data and corresponding genomic information for hundreds of cancer samples. “Today is our first glimpse of this complex interface, where genomes meet cancer medicine,” project co-leader Andrew Futreal, a human genetics researcher at the Wellcome Trust Sanger Institute, said in a statement. “By producing a carefully curated set of data to serve the cancer research community, we hope to produce a database for

ljqumpnulvkyh02yjvelbwimproving patient response during cancer treatment.” The Cancer Genome Project’s Genomics of Drug Sensitivity project is a five-year effort launched in late 2008. Researchers involved in the effort, including investigators at the Sanger Institute and the Massachusetts General Hospital Cancer Center, plan to look at how some 1,000 genetically characterized cancer cell lines respond to treatment with 400 anti-cancer treatments, alone and in combination.

Findings from studies looking at the effects of 18 anti-cancer drugs on 350 genetically characterized cancer samples are being made available to other researchers through the Cancer Genome Project’s Genomics of Drug Sensitivity web site. “By ensuring that all the drug sensitivity data and correlative analysis is freely available in an easy-to-use website, we hope to enable and support the important work of the wider community of cancer researchers,” co-project leader Ultan McDermott, a medical oncologist and human genetics researcher at the Sanger Institute, said in a statement. Along with drug sensitivity information, the team is providing genetic data on the cancer cell lines tested, including information on mutations, copy number changes, and gene expression patterns in the lines. For instance, from experiments done so far the team was able to detect some known treatment-related genetic patterns, including activating mutations in the BRAF gene in melanoma that correspond to BRAF-targeting treatment response. “It is very encouraging that we are able to clearly identify drug–gene interactions that are known to have clinical impact at an early stage in the study,” McDermott noted. “It suggests that we will discover many novel interactions even before we have the full complement of cancer cell lines and drugs screened.” “The effectiveness of novel targeted cancer agents could be substantially improved by directing treatment towards those patients that genetic study suggests are most likely to benefit, thus ‘personalizing’ cancer treatment,” Daniel Haber, director of the Massachusetts General Hospital and Harvard Medical School Cancer Center, added in a statement.

Mapping The Ozzy Genome

the ONION July 15, 2010

INFOGRAPHIC

Last month, the Cambridge, MA company Knome began mapping the complete DNA sequence for heavy metal singer and former reality star Ozzy Osbourne. Here are some of the discoveries made so far:

  • His DNA contains vast sequences of mumbly code that are almost completely indecipherableinfographic-ozzy-r_jpg_445x1000_upscale_q85
  • Subliminal genes that must be unraveled backwards
  • Brain unique in that it possesses not just opiate receptors, but powerful transmitters as well
  • Gene responsible for making Jack Daniel’s unappealing in any amount less than a fifth
  • Shares a close genetic link with no other living creature
  • Enough musical ability to get very lucky
  • Increased probability of creating, developing, and headlining Ozzfest
  • Sharon Marker: Predisposed to shuffle about shouting “Sharon!” The fact that subject is married to a person of this name is a statistically improbable coincidence

5 Signals You’re Sleep Deprived

Kaitlin Bell, Prevention, July 15, 2010

How to tell if skimping on your Zzzs is hurting your health.298x232-tired_times-298x232_tired_times

Are you in a sleep debt? Our bodies give us plenty of signals when we’re tired.

But some of us are so used to being sleep deprived that we remain oblivious to how impaired we really are. Sleep debt isn’t something you can pay off in a weekend, researchers say—it can take weeks of building up restorative sleep habits. Here are some signs you may need to make sleep a more urgent priority.